Sexton DJ, et al. - Using Irish national registry data, researchers ascertained if the incidence of nonmelanoma skin cancer (NMSC) is attenuated during periods of graft loss with a return to dialysis in those who receive multiple kidney transplants. There was a residual elevated risk in recipients of multiple kidney transplants, while the incidence of NMSC fell during periods defined by transplant failure. Although ascertainment bias may have contributed to observed trends, the overall stagnant incidence of invasive cancer highlights the need for continued cancer monitoring during graft failure.