Quan K, et al. - With a total of 19 men and 28 women with 54 unruptured intracranial aneurysms (UIAs) treated surgically, researchers explored the link between aneurysmal high-resolution vessel wall magnetic resonance imaging features and their histopathologic mechanism. Findings revealed that UIA wall enhancement was significantly associated with an irregular shape and large size. The inflammation processes of UIA walls can be demonstrated by both uniform and focal wall enhancement, although more atherosclerotic plaque formation may be indicated by the latter. Overall, the investigators suggested that new insights into the UIA wall structure assessment and treatment optimization could result from different enhancement features of high-resolution vessel wall magnetic resonance imaging being able to represent variable inflammation status of a UIA wall.