Gandhi N, et al. - Experts prospectively evaluated the performance of the SIMPLE (SIMple Disease Assessment for People with Lupus Erythematosus) index as a disease activity surrogate against physician-based disease activity measures. Findings suggested a strong correlation of SIMPLE index with formal physician assessments of disease activity in systemic lupus erythematosus (SLE), and among those without FM, the correlation was marginally higher. In places with limited physician and laboratory resources, SIMPLE index can be performed easily.