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Validating the performance of 5 risk scores for major adverse cardiac events in patients who achieved complete revascularization after percutaneous coronary intervention

Canadian Journal of Cardiology Aug 07, 2019

Zhang D, Yan R, Gao G, et al. - Among patients who achieved complete revascularization (CR) post-percutaneous coronary intervention, researchers compared previous risk scores such as the Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) score (SS), clinical SS, logistic SS (core model and extended model [LSSextended]), Age, Creatinine, and Ejection Fraction (ACEF) score, and modified ACEF score, in terms of performance. They found that mortality was not predicted by SS. Mortality prediction could be done with the help of all scores including clinical variables, particularly modified ACEF score. For myocardial infarction, the most accurate was LSSextended. Revascularization was predicted by SS and LSSextended, with marginally significant area under the receiver operating characteristic curves (AUCs). With AUCs ranging from 0.51 (ACEF score) to 0.58 (LSSextended), major adverse cardiac events (MACE) was not predicted accurately by any particular score. Overall, mortality prediction in CR patients might be aided by risk scores involving clinical variables, however, no risk scores demonstrated helpful differentiation for MACE.
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