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Utility of the relative apparent diffusion coefficient for preoperative assessment of low risk endometrial carcinoma

Clinical Imaging Mar 08, 2019

Shen Y, et al. - In this study, researchers examined the predictive ability of apparent diffusion coefficient (ADC) values in predicting patients with low risk endometrial carcinoma (EC) and identifying an optimum ADC measurement for preoperative assessment. For this investigation, they included 81 patients with stage I EC who had diffusion-weighted imaging (DWI) at 1.5T. Based on the ESMO-ESGO-ESTRO classification, patients were divided into low group and intermediate-high risk group. Between the low group and intermediate-high risk group, clinical indexes, conventional MRI parameters, minimum ADC values (minADC), mean ADC values (meanADC) and relative ADC values (rADC) were compared. Findings suggested that rADC is better than both minADC and meanADC for predicting low risk EC patients and could potentially help avoid unnecessary lymphadenectomy in the surgical management of these patients.

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