Saeed S, et al. – The researchers explored the role of technetium–99m methoxy diphosphonate (Tc–99m MDP) single photon emission tomography (SPECT) imaging for the detection of osseous invasion in craniofacial malignancies. They concluded that SPECT imaging of the skull was a very beneficial complementary form of investigation in patients with craniofacial malignancies for the assessment of osseous invasion, particularly in tumors likely to invade the skull base.