Matsuda M, Kido T, Tsuda T, et al. - In order to find out the benefit of synthetic magnetic resonance imaging (MRI) of the breast in predicting the Ki-67 status in patients with oestrogen receptor (ER)-positive breast cancer, researchers examined 49 individuals with 50 histopathologically proven breast cancers who underwent additional synthetic MRI in the present study. Applying synthetic MRI images, they obtained T1 and T2 relaxation times and their standard deviations (SD) in the breast lesions before and after contrast agent injection. Compared with the low-proliferation group, the univariate analysis revealed that the SD of T1-Gd and T2-Gd were significantly higher in the high-proliferation group. The data indicated that including an area under the receiver operating characteristic (AUROC) curve of 0.885, SD of T1-Gd was a significant and independent predictor of Ki-67 expression. The outcomes suggested that SD of T1-Gd obtained from synthetic MRI was beneficial to prognosticate Ki-67 status.