Benboujja F, et al. - For patient-tailored laryngeal recurrent respiratory papillomatosis (RRP) treatments, authors gauged the potential of combining optical coherence tomography (OCT) with laser therapy. Postoperative outcomes for patients with RRP could be improved by concurrent use of OCT imaging and laser therapy by delivering an optimal, patient-tailored treatment.

Methods

• Experts performed this in vivo study at the Massachusetts Eye and Ear Infirmary from February 1, 2017, to September 1, 2017.
• They acquired 3-dimensional OCT images before, during, and after photoangiolytic laser therapy in 10 pediatric patients with a history of papilloma growth who presented with lesions and hoarseness.
• Whether or not intraoperative OCT monitoring of changes in optical scattering and absorption provides quantitative information to control thermal damage in tissue was included in the main outcomes and measures.

Results

• As per data, among the 10 pediatric patients (age range, 4-11 years; 6 male) included in the study, epithelial hyperplasia with clear RRP lesion margins was revealed with high-resolution OCT images.
• Coagulation deep in tissue was indicated by the images acquired during therapy, and the ability to quantify the amount of tissue ablated by the photoangiolytic laser was demonstrated by the posttherapy images.