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Utility of a diffusion kurtosis model in the differential diagnosis of orofacial tumours

Clinical Radiology Feb 19, 2020

Panyarak W, Chikui T, Tokumori K, et al. - This study was conducted to examine the goodness of fit and relationships between diffusion kurtosis imaging (DKI) and a mono-exponential (ME) model, to match the corrected apparent diffusion coefficient (Dapp) and apparent kurtosis (Kapp) of the DKI model, and the apparent diffusion coefficient (ADC) of the ME model among the various orofacial lesions, and to assess the diagnostic performances between the two models. Researchers recruited a sum of 100 orofacial lesions who underwent echo-planar diffusion magnetic resonance imaging (MRI) with four b-values. Compared with the ME model, the DKI model had better goodness of fit. Furthermore, the Dapp and Kapp were also characteristic for each pathological category; though, the DKI model did not produce a significantly higher diagnostic performance compared with the ME model, which might be linked to the high association among the diffusion-derived parameters and wide variation among categories.
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