Uterocervical angle measurement for preterm birth prediction in singleton pregnant women with no history of preterm birth and normal cervical length: A prospective cohort study
European Journal of Obstetrics & Gynecology and Reproductive Biology Aug 29, 2020
Sawaddisan R, Kor-anantakul O, Pruksanusak N, et al. - Researchers investigated the predictive value of second trimester uterocervical angle (UCA) for spontaneous preterm birth (sPTB) in low-risk singleton pregnant women. Four hundred fifty singleton pregnant women with no history of sPTB and no history of second trimester miscarriage with normal cervical length (CL) who attended antenatal care at Songklanagarind Hospital, a tertiary teaching hospital in southern Thailand were made to undergo transvaginal sonographies in the second trimester. The sPTB rate was 34/421 (8.1 %) after exclusion of women with unknown pregnancy outcomes or missing UCA images. They identified the optimal UCA cut-off value of ≥ 110 degrees, which yielded a sensitivity of 83.3 % and a specificity of 61.2 %. Observations revealed the positive predictive value (PPV) of 16.7 %, negative predictive value (NPV) of 97.5 %, positive likelihood ratio (LR+) of 2.2 and negative likelihood ratio (LR-) of 0.3. They indicate that for sPTB in low risk pregnant women, the UCA in the second trimester did not exhibit a good predictive value.
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