Rana D, Wu O, Cheed V, et al. - Researchers conducted economic evaluation alongside the FEMME randomized controlled trial in order to determine the cost-effectiveness of uterine artery embolization (UAE) and myomectomy for women with symptomatic uterine fibroids wishing to avoid hysterectomy. A total of 127 premenopausal women who had symptomatic uterine fibroids were randomized to either UAE (127) or myomectomy (127). Over a 2-year time horizon, they identified correlation of UAE with higher mean costs (difference £645; 95% CI -1,381 to 2,580) and lower QALYs (difference -0.09; 95% CI -0.11 to -0.04) when compared with myomectomy. Overall small differences were evident in costs and quality-adjusted life years. Based on findings, they emphasize informing the women completely and providing them the option to choose between the two procedures.