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Using serum troponins to screen for cardiac involvement and assess disease activity in the idiopathic inflammatory myopathies

Rheumatology Mar 15, 2018

Lilleker JB, et al. - The experts aimed to investigate the utility of different serum muscle damage markers [total creatine kinase (CK), cardiac troponin T (cTnT) and cardiac troponin I (cTnI)] to identify cardiac involvement and to quantify disease activity in the idiopathic inflammatory myopathies (IIMs). They noted that in screening for cardiac involvement in IIM, serum cTnI testing could have a role. Findings suggested that abnormal levels of serum cTnT and cTnI were related to elevated disease activity, including those having a normal CK.
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