Enns EA, et al. - In this work, researchers incorporate pregnancy into a mathematical model of chlamydia transmission and determine the impact of calibrating to multiple outcomes of sexual behavior on parameter estimates and model-predicted epidemiological outcomes. While pregnancy and chlamydia in adolescents are often considered separately, both are outcomes of unprotected sexual activity. Incorporation of both as calibration targets in a model of chlamydia transmission resulted in different parameter estimates, potentially impacting the intervention effectiveness predicted by the model.