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Usefulness of findings by multimodality imaging to stratify risk of major adverse cardiac events after sepsis at 1 and 12 months

The American Journal of Cardiology Apr 15, 2020

Alnabelsi TS, et al. - This study was undertaken to investigate the the usage of left ventricular ejection fraction (LVEF) and coronary artery calcification (CAC) on nongated CT scans to distinguish septic patients at highest risk for major adverse cardiovascular events (MACE). A retrospective study was conducted to include a total of 517 adult patients with sepsis, elevated troponin levels, nongated CT scans that visualized the coronaries, and an echocardiogram. Individuals were categorized into 4 groups based on the LVEF and presence or absence of CAC. The MACE and all-cause mortality outcomes across the patient groups were compared by using the CAC negative/LVEF ≥ 50% as a control. A powerful risk stratification tool was provided by the combination of LVEF on echocardiography and CAC on nongated CT scans for predicting cardiovascular events in septic patients.

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