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Usefulness of discharge resting heart rate to predict adverse cardiovascular outcomes in patients with left main coronary artery disease revascularized with percutaneous coronary intervention –vs– coronary artery bypass grafting (from the EXCEL trial)

The American Journal of Cardiology Oct 30, 2019

Kosmidou I, Crowley A, Macedo L, et al. - Researchers examined 1,905 patients with left main coronary artery disease (LMCAD) who were randomized to percutaneous coronary intervention (PCI) with everolimus-eluting stents vs coronary artery bypass grafting (CABG) in the EXCEL trial, to determine the prognostic influence of resting heart rate (RHR) post-revascularization with PCI or CABG in this patient population. They measured RHR at discharge after the index hospitalization. The composite endpoint of mortality, myocardial infarction or stroke at 3 years was assessed as the main outcome measure. Regardless of treatment modality, a higher risk for adverse cardiovascular outcomes at 3 years was observed in relation to an increased RHR at discharge in patients with LMCAD undergoing revascularization.
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