Maddaloni E, Briganti SI, Crescenzi A, et al. - Researchers conducted this cross-sectional study to test whether the evaluation of thyroid nodules’ vascularization could improve the risk stratification ability of the American College of Radiology (ACR) TI-RADS classification system. In total, 873 thyroid nodules undergoing fine-needle aspiration have been classified according to ACR TI-RADS US classification. Three types of vascularization have been identified: type 0, no vascular signals; type 1, peripheral vascular signals; type 2, peripheral and intralesional vascular signals. According to results, the 3 vascular patterns were distributed differently within the cytology categories: 52.4% of TIR1c, 15.9% of TIR2, 5.9% of TIR3a, 6.7% of TIR3b, 12.5% of TIR4, and 28.9% of TIR5 nodules did not have vascular signals. Nodule vascularity alone was not related to a higher risk of malignant cytology, without differences between peripheral and intranodular vascularization. Color Doppler thyroid nodules study does not improve the risk stratification ability of the ACR TI-RADS US classification system.