Agrawal A, Arora A, Srivastava AK, et al. - This study was sought to evaluate the utility of tourniquet during knee arthroplasty in patients with radiographic arterial calcifications. A prospective cohort study was carried out to ascertain the incidence of tourniquet failure (inflated up to 300 mm Hg), blood transfusions, wound healing, and ischemic complications in thighs with and without arterial calcifications on preoperative radiographs, in 2,548 consecutive primary TKAs performed in the unit over a 5-year period. Eighty-six thighs exhibited vascular calcifications: 58 medial and 28 intimal. The data showed that in patients undergoing TKA, the presence of arterial calcifications on preoperative radiographs elevates the risk of tourniquet failure at 300 mm Hg, with no significant increase in rate of blood transfusions, wound healing or ischemic complications.