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Use of the probably benign (BI-RADS category 3) assessment for masses on breast MRI: Is it transferable to general clinical practice?

The Breast Journal Aug 31, 2017

Price ER, et al. – This study is performed to identify potential BI–RADS 3 mass descriptors on breast magnetic resonance imaging by systematically defining positive predictive values (PPV). The outcomes show the difficulty in transferring the theoretical concept of lesion surveillance to systematic clinical utilization.

  • For this research, they conducted a blinded retrospective review.
  • Reader 1 and reader 2 had identified 132 and 76 masses respectively in this blinded retrospective review of BI–RADS 4 masses.
  • In this study, PPV for mass descriptors and for descriptor combinations was determined.
  • No mass descriptor resulted in a PPV ≤ 2% (BI–RADS 3 threshold).
  • Descriptors with the lowest PPVs were circumscribed margin (8%), rim internal enhancement and persistent kinetics (13% each), and oval shape (15%).

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