Oshagbemi OA, et al. - Here, researchers study the risk of major osteoporotic fractures in patients with and without sarcoidosis and aim to explore the connection with average and cumulative glucocorticoid (GC) exposure and the type of major osteoporotic fractures in both these groups. Both in subjects with and without sarcoidosis, current exposure to GC is related to increased risk of major osteoporotic fractures, with no between-group difference. Sarcoidosis per se was not related to increased fracture risk. Having sarcoidosis per se, i.e., if not treated with GC, is not a risk factor for fracture, and such patients may only need risk evaluation when they commence GC therapy.