Meerwein CM, et al. - Researchers retrospectively studied 59 subjects with advanced hypopharyngeal squamous cell carcinoma to analyze the capability of various (18F)fluoro-deoxy-d-glucose (FDG)-positron emission tomography (PET)-based and magnetic resonance (MR)-based parameters so that prevertebral space (PVS) infiltration could be identified by hypopharyngeal carcinoma. They observed both the MR-based parameter of complete fat plane obliteration and PET-based models (increased SUV_max in combination with the appearance of focal FDG-uptake of prevertebral muscles; increased metabolic tumor volume [MTV]) predicting the PVS involvement individually with high accuracy.