Fougerousse AC, Mery-Bossard L, Parier J, et al. - Between October and December 2020, the authors conducted a national online practice survey to assess the modalities of methotrexate prescription for moderate to severe psoriasis by dermatologists in France. In total, 254 dermatologists responded, 237 reported prescribing methotrexate for moderate to severe psoriasis in adults, of which 57% as a first-line systemic treatment. Orally in 54.7% of cases, subcutaneously in 44.8% of cases, and intramuscularly in 0.4% of cases, methotrexate was administered. Methotrexate is prescribed by the majority of dermatologists interviewed for moderate to severe psoriasis in adults, though practices vary.