Borchard NA, et al. - Researchers evaluated patients with a history of inferior turbinate reduction, diagnosed with Empty nose syndrome (ENS) who underwent submucosal injection of carboxymethylcellulose/glycerin gel (Prolaryn) into the inferior meatuses between July 2014 and May 2018, to assess if submucosal injection of a transient, resorbable filler into the inferior meatus favorably alter nasal aerodynamics in ENS patients. Outcomes demonstrate transient, focal airway bulking via submucosal filler injection at sites of inferior turbinate tissue loss, as efficacious in providing marked benefit to ENS patients. This suggests the contributory role of aberrant nasal aerodynamics from inferior turbinate tissue loss to (potentially reversible) ENS symptoms.