Shimozono Y, Williamson ERC, Mercer NP, et al. - Researchers sought to determine the effectiveness of Extracellular Matrix Cartilage Allograft (EMCA) as an adjuvant to bone marrow stimulation (BMS) vs BMS alone in the treatment of osteochondral lesions of the talus (OLT). In retrospective cohort study, 24 patients who underwent BMS with EMCA were compared with 24 patients who were managed with BMS alone. Outcomes suggest that for the treatment of OLT, BMS with EMCA is an effective treatment approach and yields better cartilage infill in the defect on MRI. However, this did not correlate with improved functional outcomes compared with BMS alone in the short-term. Furthermore, according to the minimal clinically important difference (MCID) analysis, no significant difference was observed in clinical function scoring between either group postoperatively.