Feng-Chih Kuo, et al. - Researchers performed a retrospective study to correlate the efficacy of antimicrobial-impregnated incise drapes with non-antimicrobial-impregnated incise drapes for the prevention of periprosthetic joint infection (PJI) in individuals undergoing total joint arthroplasty (TJA). A total of 9,774 primary TJAs were recruited between 2000 and 2012. They compared individuals who received an antimicrobial-impregnated incise drape (n = 5,241) with those who received a non-antimicrobial-impregnated incise drapes (n = 4,533). Using propensity score matching, multivariate logistic regression analysis and sensitivity analysis were conducted to control for potential confounders. Notwithstanding the increasing adoption of the use of antimicrobial-impregnated incise drapes in the institute, in individuals undergoing primary TJAs, the antimicrobial-impregnated incise drapes do not decrease PJI.