Long CA, et al. - In this retrospective cohort analysis, researchers used Medicare data to assess patient, physician, and procedural features as well as cardiovascular and limb events in patients who underwent peripheral vascular intervention with drug-coated balloons. The clinical outcomes of importance were all-cause death, all-cause hospitalization, repeat femoropopliteal intervention, and major lower extremity amputation at 1 year. The observed rates of all-cause mortality, all-cause hospitalization, and major amputation at 1 year among patients who underwent femoropopliteal intervention with drug-coated balloons were found to be lower. Findings also revealed that the rates of repeat revascularization did not reduce. In this extensive study of contemporary patients in the United States, the seeming safety of drug-coated balloons was highlighted.