Mahmoodpoor A, et al. - Since patients admitted to the intensive care unit (ICU) with acute kidney injury (AKI) carry high mortality rates, researchers herein compared the efficacy of urinary and plasma neutrophil gelatinase-associated lipocalin (NGAL) levels for predicting ICU mortality in these patients. Findings showed that early progression of AKI was related to more death within 28 and 90 days. In ICU settings, while kidney health status may be assessed by one time measurement of plasma NGAL levels at the time ICU admission, this failed to serve as a reliable mortality predictor. On the other hand, it was noted that changes in plasma NGAL within 48 h of admission improved the value of this biomarker in predicting ICU mortality.