Ma T, et al. - To elucidate the consequences of FOXP4 in human breast cancer (BC), investigators evaluated its effect on BC growth, migration, and invasion by colony formation assay, CCK-8 assay, wound-healing assay, and transwell invasion assay, respectively. they performed quantitative real-time polymerase chain reaction and Western blot analyses to detect the mRNA and protein expressions of FOXP4 in BC tissue samples and cell lines. They observed promotion of cell proliferation, migration, as well as invasion of BC cells due to FOXP4. They also noted that FOXP4 facilitated the epithelial-mesenchymal transition. Overexpression of Snail partially rescued the results of FOXP4 inhibition on cancer cell migration and invasion.