Wang Y, et al. - The Taiwan Osteoporosis Association carried out a nationwide BMD survey between 2008 and 2011 using a bus equipped with a dual-energy X-ray absorptiometry machine in order to investigate the risk of fragility fracture in Taiwanese postmenopausal women with osteopenia using the hybrid intervention threshold (HIT) and Fracture Risk Assessment Tool (FRAX). A total of 13,068 postmenopausal women were recruited in the program, of which 5,743 had osteopenia and of 5,743 persons, 1,434 had high FRAX fracture risk. High fragility fracture risk was noted in one-quarter of Taiwanese postmenopausal women with osteopenia, as assessed by FRAX and HIT. Moreover, because of the poor sensitivity of BMD for fragility fracture, it was inferred that intervention for fragility fracture for postmenopausal women should also be managed by FRAX and HIT rather than BMD alone.