Ochieng WO, Ye T, Scheel C, et al. - Experts did a comparative economic study of the prices and cost-efficiency of uncrewed aircraft systems (UAS) vs motorcycles in Liberia (West Africa) for the transport of laboratory samples under simulated routine circumstances and public health danger conditions. Three UAS with operational ranges of 30 km, 65 km, and 100 km (UAS30, UAS65, and UAS100) and lifespans of 1,000 to 10,000 h were modeled the costs and number of samples transported with an authenticated motorcycle transportation program were contrasted. In this study, for the routine carrier of laboratory samples in west Africa, UAS was not a viable choice, provided the up to date level of technology, purchase prices, equipment lifespans, and operational flying ranges. Moreover, to produce more proof about UAS lifespan, failure rates, and performance under distinct climate conditions and payloads, field examinations are needed.