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Ultrasound prediction of adverse outcome and perinatal complications at diagnosis of late‐onset fetal growth restriction: A cohort study

Ultrasound in Obstetrics & Gynecology Jun 26, 2021

Dall'Asta A, Stampalija T, Mecacci F, et al. - This study was undertaken to investigate the relationship between the ultrasound parameters measured at diagnosis and perinatal adverse outcome within a cohort of late-onset fetal growth restriction (FGR) fetuses. Between 2014 and 2019, researchers designed a multicentre retrospective study including non-anomalous singleton pregnancies complicated by late-onset FGR, which was defined either by abdominal circumference (AC), estimated fetal weight (EFW) < 10th percentile for the gestation or by a reduction of the longitudinal growth of the AC by over 50 percentiles compared to an ultrasound scan performed between 18 and 32 weeks of gestation. The study enrolled 468 cases with full biometry and umbilical, middle cerebral, and uterine artery Doppler data. This study’s findings demonstrates that at diagnosis the EFW is the only sonographic parameter independently correlated with the occurrence of adverse perinatal outcomes, while a mean UtA PI MoM > 95th percentile at diagnosis is independently correlated with intrapartum distress leading to obstetric intervention.

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