Long B, et al. - Researchers evaluated the performance of endometrial thickness (ET) cut-offs for identifying endometrial cancer (EC) in women experiencing postmenopausal bleeding (PMB). Also, additional ultrasound measures, such as endometrial volume, vascular flow index, vascularization index, and uterine artery flow index, were tested for their clinical utility. They used specific MeSH terms to identify studies published between January 1990 and March 2016 in Clinicaltrials.gov and MEDLINE database via PubMed. This analysis included original, peer-reviewed cohort investigations describing EC results and specific ultrasound findings by PMB status. The pooled mean ET was found to be 16.4 mm in women with PMB and EC (n = 417). This value was 4.1 mm in women with PMB without EC. This implies that women with EC vs those without EC had a substantially higher mean ET among women with PMB. For the diagnosis of EC, an acceptable tradeoff between sensitivity and specificity was displayed by an ET cutoff of ≥ 5 mm.