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Ultrasound characterization of disordered antral follicle development in women with polycystic ovary syndrome

Journal of Clinical Endocrinology & Metabolism Sep 16, 2020

Jarrett BY, Brink HV, Oldfield AL, et al. - Researchers conducted this prospective, longitudinal study to assess follicular and endocrine characteristics of anovulatory and sporadic ovulatory cycles in women with polycystic ovary syndrome (PCOS). Participants in the study were 26 reproductive-aged women (18-38 years) with PCOS, observed during natural anovulatory (PCOS-Anov; n = 12) and sporadic ovulatory cycles (PCOS-Ov; n = 14), and 12 controls. Transvaginal ultrasonography and venipuncture were conducted in women with PCOS every other day for 4 to 6 weeks, or in control individuals at 1 interovulatory interval. According to results, follicle growth and regression have been observed on ultrasonography amidst perpetual follicular excess in PCOS. Documentation of continuous follicle recruitment and turnover, lack of persistence, and altered luteal progesterone following sporadic ovulation, provide formative details on antral follicle development in PCOS.

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