Barra F, Alessandri F, Scala C, et al. - Investigations have been done to determine the utility of three-dimensional (3D) transvaginal ultrasonography (TVS) for the diagnosis of deep endometriosis (DE). Researchers herein examined if 3D reconstructions improve the performance of TVS in determining the presence and characteristics of bladder endometriosis (BE). In this single-center comparative diagnostic accuracy study, they recruited patients with clinical suspicion of DE. In case of surgery, systematic preoperative ultrasonographic imaging was performed on the women; a conventional TVS was performed by an experienced sonographer; thereafter, a TVS, with the addition of 3D modality, was performed by another experienced sonographer, blinded to results of the previous exam. Overall, 34 out of 194 women who underwent surgery for DE were identified intraoperatively to have BE (17.5%). As per findings, ultrasound shows high accuracy for diagnosing BE. No improvement in the performance of TVS in diagnosing the presence and characteristics of BE was observed in correlation with the addition of 3D reconstructions. However, 3D ultrasound may more precisely reveal the volume of BE.