Nowak RM, et al. - Researchers determined the efficacy of a new Food and Drug Administration-approved single cardiac troponin T (cTnT) Generation 5 baseline measurement below the level of quantification (6 ng/L) and a novel study-derived baseline and 30-minute cTnT Generation 5 algorithm in excluding acute myocardial infarction in patients with suspected acute coronary syndrome in a US emergency department (ED). On analyzing patients presenting with any symptoms suspicious for acute coronary syndrome at a single US ED, it was noted that a single baseline cTnT Generation 5 measurement less than 6 mg/L and values at baseline less than 8 ng/L and a 30-minute Δ of less than 3 ng/L ruled out acute myocardial infarction in 28.8% and 41.0% of patients, respectively.