Firouzian A, et al. - The postoperative analgesic benefit of ultra–low-dose naloxone infusion was assessed, when administered as an adjuvant to patient-controlled analgesia (PCA) with morphine, in patients scheduled for lumbar discectomy. Findings demonstrated that infusion of ultra–low-dose naloxone (0.25 μg/kg/h) along with morphine PCA can significantly attenuate pain intensity, morphine consumption, and opioid-induced nausea and pruritus post- lumbar discectomy.