Zhang ZF, et al. - Researchers here aimed to determine the clinical effect of ultra-early injection (before the phase of “tooth-paste-like”) of low-viscosity cement in percutaneous vertebroplasty (PVP) for treating osteoporotic vertebral compression fractures (OVCFs). Findings suggested that in comparison to the traditional injection procedure, ultra-early injection of low-viscosity cement during PVP procedures in the treatment of OVCFs quickly and significantly relieved pain, reduced the incidence of adjacent vertebral fractures, prevented progressive kyphotic deformity and also did not increased the risk of cement leakage.