Ho-Pham LT, et al. - Authors ascertained the relationship between type 2 diabetes (T2D) and bone architecture and measures of bone strength. A total of 1115 women and 614 men aged ≥ 30 were randomly recruited from Ho Chi Minh City. They derived the polar stress-strain index (pSSI) from the peripheral quantitative computed tomography (pQCT) measurements. The prevalence of T2D was seen to be ~ 8%. Findings suggested greater trabecular but lower cortical volumetric bone density (vBMD) which leads to lower bone strength in patients with T2D vs non-diabetic individuals.