Würnschimmel C, Kachanov M, Wenzel M, et al. - This study was intended to present 20 year trends in prostate cancer stage and grade migration in a large contemporary German radical prostatectomy cohort. Researchers distinguished prostate cancer (PCa) patients treated with radical prostatectomy between 2000 and 2020 (n = 21,646). They estimated the estimated annual percentage change for D'Amico risk groups, biopsy Gleason Grade Group, PSA and cT stage as well as postoperative RP GGG and pT stage relying on log linear regression methodology. The data validate the trend towards less frequent treatment of low risk PCa and more frequent treatment of high risk PCa, also after adjustment for number of biopsy cores.