Lou E, et al. - In a prospective observational study, researchers examined women diagnosed with ovarian cancer (n=24, mean (SD) age was 62.0 (8.1) years), to assess whether tumor-stroma proportion can serve as a predictive biomarker of chemoresistance in these patients. As per the evidence generated in this study, there exists a link between tumor-stroma proportion at initial diagnosis of ovarian carcinoma and eventual emergence of platinum chemoresistance. High tumor-stroma proportion was found in 4 of 5 (80.0%) platinum-resistant ovarian tumors, conversely a tumor-to-stroma proportion of 50% or greater was found in 5 of 19 (26.3%) platinum-sensitive tumors. As already prepared slides used for routine histopathologic evaluation were utilized, this assessment was not cost-prohibitive, and was rather straightforward, and this parameter can be incorporated in pathology reports as a component of the medical record.