Malakorn S, Ouchi A, Hu CY, et al. - In metastatic colon cancer, right-sided primary tumor location is correlated with worse prognosis, but the impact of sidedness on non-metastatic disease is less well known, so researchers assessed if sidedness has any impact on recurrence or survival among patients with localized colon cancer. Consecutive patients who underwent curative colon cancer resection (2006-2013) were found in a prospective database and analyzed retrospectively. Six hundred seventy-three patients, 347 with right-sided disease, were evaluated in this analysis. According to findings, tumor sidedness was not related to recurrence risk in patients with colon cancer who had curative resection. However, right-sidedness was correlated with unique recurrence patterns and lower survival following recurrence among patients who developed recurrence. Treatment stratification should not be based on only tumor sidedness in patients presenting with localized disease.