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Triclosan and triclocarban exposure and thyroid function during pregnancy - A randomized intervention

Reproductive Toxicology Sep 27, 2017

Ley C, et al. - This study is performed to figure out if Triclosan and triclocarban (TC) exposure from wash products or urinary triclosan level modified thyroid function amid pregnancy or anthropometric measurements at birth. According to the outcome obtained, TCs from wash products, primarily liquid and bar soaps, did not affect thyroid function measures amid pregnancy or babies' anthropometric measures at delivery.

  • For this study, they conducted a randomized intervention.
  • This was the study of wash products with or without TCs, including toothpaste.
  • In this study, they enrolled pregnant women from 20 weeks’ gestation.
  • Urinary triclosan, TSH, T4 and T3 were evaluated at enrollment, 36 weeks’ gestation and/or post-delivery; anthropometric measures at birth were ascertained from medical records. 78 and 76 mothers were assigned to the TC-containing and no-TC-containing product arms, respectively.
  • No differences were seen in any thyroid function measure at any time point or in any anthropometric measurement at birth between either exposure arms or lowest and highest urinary triclosan quartile groups.

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