Pieri M, De Simone A, Rose S, et al. - Researchers analyzed current evidence from randomized trials regarding interventions examined in the prevention or management of delirium in adult patients undergoing cardiac surgery. They analyzed data from 56 randomized controlled trials that studied 38 interventions. These trials were identified from PubMed and the Cochrane and Scopus databases. The treatment with dexmedetomidine, ketamine, antipsychotics, glucocorticoids, propofol, opioids, volatile anesthetics, local anesthetics, and remote ischemic preconditioning constituted the most commonly examined strategies. They noted the extremely heterogenous nature of the analyzed strategies. The agent that was most frequently examined was dexmedetomidine and it was suggested to be able to possibly reduce the occurrence of delirium following cardiac surgery.