Michael Fang, Ph.D., Dan Wang, et al. - This study was carried out to evaluate trends in diabetes treatment and control in US adults, 1999–2018. Researchers performed a cross-sectional analysis of data from adults with diabetes in the United States participating in the National Health and Nutrition Examination Survey (NHANES) to evaluate national trends in diabetes treatment and risk-factor control from 1999 through 2018. The percentage of adult NHANES participants with diabetes in whom glycemic control (glycated hemoglobin level, < 7%) was achieved declined from 57.4% (95% confidence interval [CI], 52.9 to 61.8) to 50.5% (95% CI, 45.8 to 55.3) between the 2007–2010 period and the 2015–2018 period. Glycemic and blood-pressure control declined in adult NHANES participants with diabetes, while lipid control leveled off after more than a decade of progress from 1999 to the early 2010s.