Surrey ES, et al. - This article was written with the objective to compare outcome for women who received either procedure within the first year post initial surgery. The outcome of this study demonstrated significantly different 1-year post-surgical outcomes for patients who underwent an endometriosis-related hysterectomy relative to a laparoscopy. Moreover, the endometriosis patients in this investigation had a considerable risk of surgical complications, subsequent surgeries, and hospital admissions, both amid and after their initial therapeutic laparoscopy or hysterectomy.

Methods

• From 2004 to 2013, data from the Truven Health MarketScan claims databases were utilized to identify women aged 18-49 years who received an endometriosis-related laparoscopy or hysterectomy.
• In this study, patients were excluded if they did not have continuous insurance coverage from 1 year before through 1 year after their endometriosis-related procedure, if they were diagnosed with uterine fibroids prior to or on the date of surgery (i.e., index date), or if they had a hysterectomy prior to the index date.
• The descriptive investigations analyzed differences between patients with an endometriosis-related laparoscopy or hysterectomy regarding medications prescribed, complications, and hospitalizations amid the immediate year post procedure.

Results

• In this study, the final sample comprised of 24,915 women who underwent a hysterectomy and 37,308 who underwent a laparoscopy.
• Results uncovered significant differences between the cohorts, with women who received a laparoscopy more likely to be recommended a GnRH agonist, progestin, danazol, or an opioid analgesic in the immediate year post procedure compared to women who underwent a hysterectomy.
• In contrast, women who underwent a hysterectomy generally had higher complication rates.
• Index hospitalization rates and length of stay (LOS) were higher for women who had a hysterectomy, while post-index hospitalization rates and LOS were higher for women who had a laparoscopy.
• Post-procedure complications were related to significantly higher hospitalization rates and longer LOS for both cohorts.