Treatment outcomes associated with dupilumab use in patients with atopic dermatitis
JAMA Dec 18, 2021
Strober B, Mallya UG, Yang M, et al. - In patients with atopic dermatitis (AD), dupilumab use was found to be linked with early (1 month) of patient-reported benefits that were maintained after 12 months of therapy.
A total of 699 patients with AD who initiated dupilumab treatment were included in this prospective, longitudinal study in the clinical practice setting, to assess self-reported disease control and quality of life of these patients after initiating dupilumab.
In the majority of the patients, adequate disease control (Atopic Dermatitis Control Tool total score) was achieved at month 1 with further improvement at month 12.
Compared to baseline, a reduction in the use of other AD therapies was evident at each follow-up.
With AD treatment, patient satisfaction was higher vs baseline at each follow-up to 85.1% at month 12.
At each follow-up, reductions in flares, itch, skin symptoms, and improvements in sleep, health-related quality of life, and daily activities, relative to baseline, were experienced by patients.
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