Treatment of neurotrophic keratopathy with minimally invasive corneal neurotisation: Long-term clinical outcomes and evidence of corneal reinnervation
British Journal of Ophthalmology Feb 22, 2019
Catapano J, et al. - At The Hospital for Sick Children, Toronto, Canada, between November 2012 and February 2017, 19 eyes of 16 subjects were prospectively studied to describe clinical outcomes of corneal innervation in neurotrophic keratopathy (NK) cases treated with minimally invasive corneal neurotisation (MICN) using a sural nerve graft and donor sensory nerves from the face. They noted improvement in mean central corneal sensation (CCS) from 0.8±2.5 mm to 49.7±15.5 mm at final follow-up. They observed stabilization of the corneal epithelium with MICN along with permitting optical keratoplasty for subjects with NK-related corneal opacity when an alternative source of innervation was provided.
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