Stagg HR, et al. – The comparative efficacy and harms of latent tuberculosis infection (LTBI) treatment regimens targeting the prevention of active tuberculosis (TB) among adults and children was contemplated in this study. This study yielded evidence for the efficacy and safety of 6–month isoniazid monotherapy, rifampicin monotherapy, and combination therapies with 3 to 4 months of isoniazid and rifampicin.