Bernstein EF, et al. - For the treatment of acne scars, researchers here investigated the utility of fractional treatment with a dual wavelength 1,064 and 532 nm picosecond-domain laser, delivering a 10 × 10 array of highly focused beamlets via a holographic optic. In this work, the 1,064 and 532 nm picosecond-domain laser incorporating a 10 × 10 holographic beam-splitting handpiece proved safe and effective for the treatment of facial acne scars. The treatments were well tolerated and the subjects experienced little to no downtime.