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Treatment and survival of locally recurrent rectal cancer: A cross-sectional population study 15 years after the Dutch TME trial

European Journal of Surgical Oncology Jun 21, 2019

Detering R, et al. - Researchers performed a cross-sectional population study of a total of 107 locally recurrent rectal cancer (LRRC) patients (5.1%) evaluating their treatment and overall survival (OS). From a collaborative Snapshot study on 2095 surgically treated rectal cancer patients from 71 Dutch hospitals in the year 2011, they selected the patients and stratified them for prior preoperative radiotherapy (PRT) and intention of treatment of LRRC. PRT for the primary tumor was undertaken in 88 (82%) patients. Outcomes revealed no significant association of prior PRT with survival after diagnosis of LRRC. Among patients who developed local recurrence following curative resection in 2011, 29% were amenable for again curative-intent treatment, with a corresponding median survival of 22 months.
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