Pirelli L, et al. - Researchers undertook this study to examine the efficacy and safety of Transinnominate (TI) transcatheter aortic valve replacement (TAVR) as an alternative access in patients with severe aortic stenosis not amenable to a transfemoral approach. They recognized TI approach as a safe, reproducible and minimally invasive hybrid technique for TAVR in high-risk patients. In their early experience, minimal surgical trauma and perioperative complications were evident with rapid patient recovery.